Main Menu

Marker for animal by-products

Regulation (EC) No 1069/2009 lays down public health and animal health rules for animal by-products and derived products not intended for human consumption, in order to prevent and minimise risks to public and animal health arising from those products, and in particular to protect the safety of the food and feed chain. It sorts animal by-products into three categories according to the associated risk. In addition, specifies under which conditions animal by-products may be used for applications in animal feed and for various purposes, such as in cosmetics, medicinal products and technical applications. It also lays down obligations for operators to handle animal by-products within establishments and plants which are subject to official controls.

Commission Regulation (EU) No 142/2011 lays down implementing measures for the public and animal health rules for animal by- products and derived products and specifies the requirements regarding collection, transport, identification and traceability of animal by-products. Furthermore, derived products from Category 1 and Category 2 material shall be permanently marked with glyceroltriheptanoate (GTH) to ensure they not enter the feed and food chain. The operators of processing plants shall have in place a system of monitoring and recording of parameters suitable to demonstrate to the competent authority that the required homogeneous minimum concentration of at least 250 mg GTH per kg fat is achieved.

The availability of the marker and the corresponding analytical method with a proven performance profile is an important prerequisite for lifting the total feed ban, thus allowing Category 3 animal by-products to be used in animal nutrition.

The JRC-IRMM has been actively involved in the identification, testing and implementation of the GTH marker that has been proposed by the JRC. GTH has been tested in cooperation with the rendering industry and approved by the Commission via its Standing Committee on the Food Chain and Animal Health.

Boix, A., Serano, F., Bellorini, S. and von Holst, C., Implementation study to evaluate glyceroltriheptanoate (GTH) as a maker for animal by-products in rendering systems[3Mb] 


A method for the detection of GTH processed products from Category 1 and Category 2 materials

JRC-IRMM developed a method for the detection of GTH in meat and bone meal (MBM) and rendered fat. The method is based on gas chromatography coupled to mass spectrometry (GC-MS) and has been successfully validated via a collaborative study. 

Determination of glyceroltriheptanoate (GTH) in processed animal by-products by gas chromatography - 6th edition [454Kb]

Von Holst C, Boix Sanfeliu A, Bellorini S, Serano F, Androni S, Verkuylen B, Margry R.  Use of Glyceroltriheptanoate as Marker for Processed Animal By-Products: Development and Validation of an Analytical Method. Food Additives and Contaminants 26 (4); 2009. p. 466-474.

Boix Sanfeliu A, Bellorini S, Von Holst C. Validation of an Analytical Method for the Determination of Glycerolthiheptanoate (GTH) in Processed Animal By-products: Results of a Collaborative Study. Food Additives and Contaminants 27 (6); 2010. p. 793-800.

Latest update 1 March, 2006

News archive